毛晓霞,女,1984年9月生,河南洛阳人,博士,副教授,环境科学专业硕士生导师,主要从事环境污染物检测工作,主持了5项科研项目。发表论文28篇,全部为SCI论文,其中SCI一区论文6篇,封面文章2篇。申请专利2项。入选的人才计划安徽省拔尖人才项目。
邮箱:absd25@126.com
研究方向:污染物检测、生物传感
承担项目:
1.主持,2018年国家自然科学基金青年项目,“纳米模拟酶-DNA水凝胶”催化体系的构建及其在生物医学分析中的应用
2.主持,2019年高校优秀拔尖人才培育资助项目
3.主持,2017年上海市能源作物育种及应用重点建设实验室开放课题,能源作物葡萄糖代谢水平的检测研究
4.主持,2019年横向课题,与安庆虹泰新材料有限责任公司合作,植物油酸深加工工艺改进
5.主持,2013年冠军白菜青年科研基金,激素对竹柳扦插育苗的影响研究,
学术及科研成果:(以近五年的为主)
论文:
1.Xiaoxia Mao#, Dongsheng Mao#, Juanjuan Jiang, Benyue Su, Guifang Chen*, Xiaoli Zhu*. A semi-dry chemistry hydrogel-based smart biosensing platform for on-site detection of metal ions.Lab on a Chip, 2021,21, 154-162.(SCI一区)
2. Xiaoxia Mao#, Dongsheng Mao#, Tianshu Chen, Mohammed Jalalah, Mohammed S. Al-Assiri,Farid A. Harraz,* Xiaoli Zhu,* and Genxi Li. DNA hydrogel-based three-dimensional electron transporter and its application in electrochemical biosensing. ACS Appl. Mater. Interfaces 2020, 12, 36851−36859.(SCI一区,封面文章)
3. Yang YM#, Liu SW#, Cui XF, Yang L, Zhang JL, Mao XX*, Gao YC*. Sensitive on-site detection of miRNA based on enzyme-propelled multiple photoinduced electron transfer strategy.Microchim Acta 2021
3.Xiaoxia Mao, Shaowei Liu, Benyue Su, Dejin Wang, Zhan Huang, Jian Li, Yuanguang Zhang*, Luminescent europium(III)-organic framework for visual and on-site detection of hydrogen peroxide via a tablet computer. Microchim Acta. 2020 187, 416.
4.Xiaoxia Mao#,Guifang Chen#, Zihan Wang, Yuanguang Zhang, Xiaoli Zhu*, Genxi Li*. Surface-immobilized and self-shaped DNA hydrogels and their application in biosensing.Chem. Sci., 2018, 9, 811−818. (IF = 9.346,封面文章,SCI一区)
5.Xiaoxia Mao, Shaobing Pan, Duoqi Zhou, Xiaowu He, Yuanguang Zhang*. Fabrication of DNAzyme-functionalized hydrogel and its application for visible detection of circulating tumor DNA.Sens. Actuators B Chem. 2019, 285, 385−390. (IF = 7.100,SCI一区)
6.Xiaoxia Mao, Yifei Li, Peng Han, Xiaohong Wang, Shiqi Yang, Fan Zhang, Xiuqing Gong*, Ya Cao*. One-pot and one-step colorimetric detection of aminopeptidase N activity based on gold nanoparticles-based supramolecular structure.Sens. Actuators B Chem. 2018, 267, 336−341. (IF = 7.100,SCI一区)
7.Xiaoxia Mao, Siyu Liu, Chao Yang, Fengzhen Liu, Keming Wang*, Guifang Chen*. Colorimetric detection of hepatitis B virus (HBV) DNA based on DNA-templated copper nanoclusters.Anal. Chim. Acta, 2016, 909, 101−108. (IF = 5.977,SCI一区)
8.Xiaoxia Mao, Yuzhi Hong, Zongze Shao, Yan Zhao, Ziduo Liu*. A novel cold-active and alkali-stable β-glucosidase gene isolated from the marine bacteriumMartelella mediterranea.Appl. Biochem. Biotechnol., 2010, 162, 2136−2148.
9. Xiaoli Zhu#,Xiaoxia Mao#, Zihan Wang, Chang Feng, Guifang Chen*, Genxi Li*. Fabrication of nanozyme@DNA hydrogel and its application inbiomedical analysis.Nano Res., 2017, 10, 359−970. (IF =8.183,SCI一区,并列一作)
10. Hai Shi,Xiaoxia Mao, Xiaoxia Chen, Zihan Wang, Keming Wang*, Xiaoli Zhu*. The analysis of proteins and small molecules based on sterically tunable nucleic acid hyperbranched rolling circle amplification.Biosens. Bioelectron., 2017, 91,136−142.
11. Chang Feng,Xiaoxia Mao, Hai Shi, Bing Bo, Xiaoxia Chen, Tianshu Chen, Xiaoli Zhu*, and Genxi Li*. Detection of microRNA: A point-of-care testing method based on a pH-responsive and highly efficient isothermal amplification.Anal. Chem., 2017, 89, 6631−6636.
12. Chang Feng,Xiaoxia Mao, Yucai Yang, Xiaoli Zhu*, Yongmei Yin*, Genxi Li*. Rolling circle amplification in electrochemical biosensor with biomedical applications.J. Electroanal. Chem., 2016, 781, 223−232.
13. Chang Feng, Bing Bo,Xiaoxia Mao, Hai Shi, Xiaoli Zhu*, Genxi Li*. From interface to solution: Integrating immunoassay with netlike rolling circle amplification for ultrasensitive detection of tumor biomarker.Theranostics 2017, 7, 31−39.
14. Zhuxin Wang, Peng Han,Xiaoxia Mao, Yongmei Yin*, Ya Cao*. Sensitive detection of glutathione by using DNA-templated copper nanoparticles as electrochemical reporters.Sens. Actuators B Chem., 2017, 238, 325−330.
15. Yun Lv, Lili Yang,Xiaoxia Mao, Mengjia Lu, Jing Zhao*, Yongmei Yin*. Electrochemical detection of glutathione based on Hg2+-mediated strand displacement reaction strategy.Biosens. Bioelectron., 2016, 85, 664−668.
16. Chao Li, Xiaolu Hu, Jianyang Lu,Xiaoxia Mao, Yang Xiang, Yongqian Shu, Genxi Li*. Design of DNA nanostructure-based interfacial probes for electrochemical detection of nucleic acid directly in whole blood.Chem. Sci., 2018, 9, 979−984.
17. Jiepei Cao, Wang Wei, Bing Bo,Xiaoxia Mao, Keming Wang*, Xiaoli Zhu*, A dual-signal strategy for the solid detection of both small molecules and proteins based on magnetic separation and highly fluorescent copper nanoclusters,Biosens. Bioelectron. 2017, 90, 534−541.
18. Chao Li, Liu Shi, Yaqin Tao,Xiaoxia Mao, Yang Xiang*, Genxi Li*. Flexible regulation of DNA displacement reaction through nucleic acid-recognition enzyme and its application in keypad lock system and biosensing.Sci. Rep., 2017, 7, 10017.
19. Yue Huang, Hao Li, Lei Wang,Xiaoxia Mao, Genxi Li*. Highly sensitive protein detection based on smart hybrid nanocomposite-controlled switch of DNA polymerase activity.ACS Appl. Mater. Interfaces, 2016, 8, 28202−28207.
20. Xiaoli Zhu, Siyu Liu, Jiepei Cao,Xiaoxia Mao, Genxi Li*. Switchable DNA wire: Deposition-stripping of copper nanoclusters as an "ON-OFF" nanoswitch.Sci. Rep., 2016, 6, 19515−19515.
21. Zhuxin Wang, Yifei Li, Peng Han,Xiaoxia Mao, Yongmei Yin*, Ya Cao*. Binding-responsive catalysis of Taq DNA polymerase for the sensitive and selective detection of cell-surface proteins.Chem. Commun., 2016, 52, 10684−10687.
22. Ya Cao, Zihan Wang, Jiepei Cao,Xiaoxia Mao, Guifang Chen*, Jing Zhao*. A general protein aptasensing strategy based on untemplated nucleic acid elongation and the use of fluorescent copper nanoparticles: Application to the detection of thrombin and the vascular endothelial growth factor.Microchim. Acta, 2017, 184, 3697–3704.
23. Dan Wu, Tao Gao, Lin Lei, Dawei Yang,Xiaoxia Mao, Genxi Li*. Colorimetric detection of proteins based on target-induced activation of aptazyme.Anal. Chim. Acta, 2016, 42, 68−73.
24. Dan Wu, Chao Li, Xiaolu Hu,Xiaoxia Mao, Genxi Li*. Electrochemical detection of DNA 3'-phosphatases based on surface-extended DNA nanotail strategy,Anal. Chim. Acta, 2016, 924, 29−34.
25. Fangfang Ban, Hai Shi, Chang Feng,Xiaoxia Mao, Yongmei Yin*, Xiaoli Zhu*. A one-pot strategy for the detection of proteins based on sterically and allosterically tunable hybridization chain reaction.Biosens. Bioelectron., 2016, 86, 219−224.
26. Qiongxuan Fan, Chao Li, Yaqin Tao,Xiaoxia Mao, Li Genxi*. Simple and fast screening of G-quadruplex ligands with electrochemical detection system.Talanta, 2016, 160, 144−147.
27. Tao Gao, Chaoli Mu, Hai Shi, Liu Shi,Xiaoxia Mao, Genxi Li*. Embedding capture-magneto-catalytic activity into a nanocatalyst for the determination of lipid kinase.ACS Appl. Mater. Interfaces, 2018, 10, 59–65.
28. Jing Zhao, Yingying Tang, Ya Cao, Tianshu Chena, Xiaoxia Chen,Xiaoxia Mao, Yongmei Yin*, Guifang Chen*. Amplified electrochemical detection of surface biomarker in breast cancer stem cell using self-assembled supramolecular nanocomposites.Electrochim. Acta, 2018, 283, 1072−1078.
专利:
1.毛晓霞,闫鸿远,朱小立,毛东升,杨雨濛,一种基于智能DNA水凝胶的汞离子现场检测新方法,专利申请号:202011096834.9
2.毛晓霞,金宝石,操璟璟,周葆华,赵宽,崔晓峰,一种基于铕基金属有机骨架材料Eu-MOF的过氧化氢的现场检测方法,专利申请号:202010191968.2;已进入实审阶段
科研获奖:
1、2018年安徽省教学成果奖三等奖,以“互联网+”老员工创新创业大赛为平台,推进创新创业教育,提升老员工创新创业能力
2、2017年安徽省“互联网+”老员工创新创业大赛创意组铜奖
3、2020年冠军白菜第六届中国国际“互联网+”老员工创新创业大赛三等奖